Abstract
Purpose
The triticeal cartilage, situated within the lateral thyrohyoid membrane, remains elusive in function yet crucial in clinical contexts. Composed of hyaline cartilage, it is prone to ossification, potentially leading to diagnostic challenges such as misidentification with atherosclerosis or fractures.
Methods
This study, aiming to establish its prevalence and highlight clinical relevance, conducted a systematic review across several electronic databases such as Medline, PUBMED, Scopus, Google Scholar, Web of Science, SpringerLink and Sciencedirect using keywords “triticeal cartilage”, “triticeous cartilage” or “cartilago triticea”. An assurance tool for anatomical investigations was used to assess the quality of the methodology (AQUA). A random effects model was utilized to determine the pooled prevalence.
Results
The true prevalence of triticeal cartilage was found to be variable, with an overall pooled proportion of 43% while crude prevalence were 50.6%. Its crude prevalence was notably higher in women compared to men, in contrary true prevalence was higher in men, posing sex-related disparities. It was mostly seen bilaterally. When the morphologic characteristics of the cartilage were evaluated, classification differences were observed in terms of shape, with a mean length of 5.48 mm, a mean width of 3.04 mm and a mean weight of 62.32 mg. The vertebral level at which the TC was located was mostly C4. The degree of calcification of the cartilage was most commonly mild.
Conclusion
In conclusion, triticeal cartilage holds significant clinical importance, necessitating vigilance during diagnostic evaluations and surgical approaches. Further studies are imperative to elucidate its function comprehensively and refine diagnostic strategies, ensuring optimal patient care in neck-related pathologies.
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Data availability
No datasets were generated or analysed during the current study.
References
-
Standring S (2021) Gray’s Anatomy E-Book: Gray’s Anatomy E-Book. Elsevier Health Sciences
-
Depreli A, Simsek SB, Sonmez S, Dogan B, Ozgen MN, Orgev BK, Irmak Sapmaz H (2024) Investigation of triticeal cartilage anatomy in forensic autopsy cases. Surg Radiol Anat :1–6
-
Watanabe H, Kurihara K, Murai T (1982) A morphometrical study of laryngeal cartilages. Med Sci Law 22:255–260
-
Wilson I, Stevens J, Gnananandan J, Nabeebaccus A, Sandison A, Hunter A (2017) Triticeal cartilage: the forgotten cartilage. Surg Radiol Anat 39:1135–1141
-
Alqahtani E, Marrero DE, Champion WL, Alawaji A, Kousoubris PD, Small JE (2016) Triticeous cartilage CT imaging characteristics, prevalence, extent, and distribution of ossification. Otolaryngol Head Neck Surg 154:131–137
-
Di Nunno N, Lombardo S, Costantinides F, Di Nunno C (2004) Anomalies and alterations of the hyoid-larynx complex in forensic radiographic studies. Am J Forensic MEd Pathol 25:14–19
-
Henriques JCG, Kreich EM, Baldani MH, Luciano M, de Melo Castilho JC, de Moraes LC (2011) Panoramic radiography in the diagnosis of carotid artery atheromas and the associated risk factors. Open Dent J 5:79
-
Henry BM, Tomaszewski KA, Walocha JA (2016) Methods of evidence-based anatomy: a guide to conducting systematic reviews and meta-analysis of anatomical studies. Ann Anat 205:16–21
-
Yammine K (2014) Evidence-based anatomy. Clin Anat 27:847–852
-
Page MJ, Moher D, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, Shamseer L, Tetzlaff JM, Akl EA, Brennan SE (2021) PRISMA 2020 explanation and elaboration: updated guidance and exemplars for reporting systematic reviews. BMJ 372
-
Henry BM, Tomaszewski KA, Ramakrishnan PK, Roy J, Vikse J, Loukas M, Tubbs RS, Walocha JA (2017) Development of the anatomical quality assessment (AQUA) tool for the quality assessment of anatomical studies included in meta-analyses and systematic reviews. Clin Anat 30:6–13
-
Ara A, Rahman M, Ara Z, Chowdhury Al, Begüm T, Chowdhury M, Faziletunnesa (2012) The incidence of cartilago triticea in Bangladeshi cadaver. CBMJ 1:8–10
-
Emre E, Akkoc R, Ogeturk M (2022) Prevalence and distribution of triticeal cartilage. Folia Morphol (Praha) 81:150–156
-
Pinheiro J, Cascallana JL, de Abajo BL, Otero JL, Rodriguez-Calvo MS (2018) Laryngeal anatomical variants and their impact on the diagnosis of mechanical asphyxias by neck pressure. Forensic Sci Int 290:1–10
-
Gharehdaghi J, Barzegar Bafroei A, Hedayatshodeh M (2022) Examining the prevalence and Morphological Diversity of Triticeal Cartilage and its importance in Cadavers referred to Tehran Anatomy Hall, Iran. Iran J Forensic Med 27:229–234
-
Joshi MM, Joshi SD, Joshi SS (2014) Prevalence and variations of cartilago triticea. Int J Anat Res 2:474–477
-
Koca R, Fazliogullari Z, Kelesoglu K, Koplay M, Karabulut AK (2020) Prevalence and clinical significance of the triticeal cartilage. Anatomy 14:97–101
-
Senanayake S (2015) Prevalence and features of triticea cartilage in an autopsy sample of tertiary care hospital in Sri Lanka. Medico-Legal J Sri Lanka 2
-
Vatansever A, Demiryürek D, Tatar İ, Özgen B (2018) The triticeous cartilage—redefining of morphology, prevalence and function. Folia Morphol (Praha) 77:758–763
-
Tubbs RS, Dixon JF, Loukas M, Shoja MM, Cohen-Gadol AA (2010) Relationship between the internal laryngeal nerve and the triticeal cartilage: a potentially unrecognized compression site during anterior cervical spine and carotid endarterectomy operations. Oper Neurosurg 66:ons187–ons190
-
Ajmani M (1990) A metrical study of the laryngeal skeleton in adult nigerians. J Anat 171:187
-
Pandit R, Yadav PK, Sharma N (2022) Prevalence of triticeous cartilage: a descriptive cross-sectional study. J Univers Coll Med Sci 10
-
Naimo P, O’Donnell C, Bassed R, Briggs C (2013) The use of computed tomography in determining developmental changes, anomalies, and trauma of the thyroid cartilage. Forensic Sci Med Pathol 9:377–385
-
Alsarraf R, Mathison S, Futran N (1998) Symptomatic presentation of an enlarged, ossified triticeal cartilage. Am J Otolaryngol 19:339–341
-
Munhoz L, da Silva Costa CL, Júnior NA, Monteiro SAC, Arita ES, Watanabe PCA (2019) Triticeal cartilage calcification: radiographic features in plain radiographs. Clinical and Laboratorial Research in Dentistry
-
Grossman JW (1945) The triticeous cartilages. A roentgen-anatomic study. Am J Roentgenol 53:166–170
-
Ciofalo A, Fatuzzo I, Lo Re F, Gilardi A, Messineo D, Greco A, de Vincentiis M (2022) A silent laryngeal trauma case: an unexpected late fracture of the superior portion of the thyroid cartilage superior horn. Ear, Nose & Throat Journal:01455613221115119
-
Bhatia PL, Dutta NK, Sanasam JC (1979) Osteonecrosis of hyoid bone and thyroid cartilage. Arch Otolaryngol 105:553–554
Acknowledgements
The authors would like to thank Prof. Güven Özkaya for his contribution to the statistical analysis of the article.
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Ilgaz, H.B., Vatansever, A. Triticeal cartilage: a meta-analysis of prevalence and morphologic evaluation. Surg Radiol Anat (2024). https://doi.org/10.1007/s00276-024-03431-9
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DOI: https://doi.org/10.1007/s00276-024-03431-9